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Crosstalk Between Estrogen and Leptin Signalling in the Hypothalamus

Gao Q, Horvath T. Crosstalk between estrogen and leptin signaling in the hypothalamus. Am J Physiol Endocrinol Metab. 2008 Mar 11 [Epub ahead of print]

Comparative Medicine, Yale University, New haven, Connecticut, United States.

Obesity, characterized by enhanced food intake (hyperphagia) and reduced energy expenditure that results in the accumulation of body fat, is a major risk factor for various diseases including diabetes, cardiovascular disease and cancer.… Read More

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Limited Synthesis Polyunsaturates in Adults

Plourde M, Cunnane SC. Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements. Appl Physiol Nutr Metab. 2007 Aug;32(4):619-34.
There is considerable interest in the potential impact of several polyunsaturated fatty acids (PUFAs) in mitigating the significant morbidity and mortality caused by degenerative diseases of the cardiovascular system and brain.… Read More

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The Influence of the Subject’s Training State on the Glycemic Index.

Mettler S et. al. The influence of the subjects’ training state on the glycemic index.  Eur J. Clin Nutr (2007 ) Jan;61(1):19-24.

Objective:To determine the glycemic index (GI) dependence on the training state of healthy adult males.Subjects and design:Young, adult males of normal body mass index and normal glucose tolerance were tested twice with a 50 g reference glucose solution and twice with a breakfast cereal containing 50 g of available carbohydrates in a randomized order.… Read More

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Does Cumulating Endurance Training at the Weekends Impair Training Effectiveness?

Meyer T Does cumulating endurance training at the weekends impair training effectiveness? Eur J Cardiovasc Prev Rehabil. 2006 Aug;13(4):578-84.

BACKGROUND: Due to occupational restrictions many people’s recreational endurance activities are confined to the weekends. We intended to clarify if cumulating the training load in such a way diminishes endurance gains. DESIGN: We conducted a longitudinal study comparing training-induced changes within three independent samples.… Read More

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Different Glycemic Indexes of Breakfast Cereals Are Not Due to Glucose Entry into Blood but to Glucose Removal by Tissue.

Schenk S et. al. Different glycemic indexes of breakfast cereals are not due to glucose entry into blood but to glucose removal by tissue.  Am J Clin Nutr. (2003) 78(4):742-8.

BACKGROUND: The glycemic index (GI) of a food is thought to directly reflect the rate of digestion and entry of glucose into the systemic circulation.… Read More