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Does the EC Stack Stop Working

Last week, I answered a Q&A about ephedrine and caffeine (the EC stack) and how long it can be used.  And in that piece I made a throwaway/unexplained statement of:

I do mean that this is unusual in that most drugs lose, or at least appear to lose, their effect over time (it’s a little more complicated than this but I’ll save my explanation of this statement for next week or something).

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